Abstract
Nine carbapenem-resistant Escherichia coli isolates harboring Klebsiella pneumoniae carbapenemase (KPC)-2 or KPC-3 enzymes were identified in patients residing in 7 distinct long-term care facilities. Cefotaxime-hydrolyzing (CTX-M)-type beta-lactamases were also documented in 3 isolates. The identification of these enzymes in patients staying in long-term care facilities should be of great concern to all components of health care systems.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism
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Carbapenems / pharmacology*
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Escherichia coli / drug effects*
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Escherichia coli / enzymology*
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Escherichia coli / genetics
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Humans
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Klebsiella pneumoniae / enzymology
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Klebsiella pneumoniae / genetics*
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Long-Term Care*
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beta-Lactam Resistance*
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beta-Lactamases / genetics
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beta-Lactamases / metabolism
Substances
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Bacterial Proteins
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Carbapenems
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beta-Lactamases
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carbapenemase