MRI of hepatic adenomatosis: initial observations with gadoxetic acid contrast agent in three patients

AJR Am J Roentgenol. 2008 May;190(5):W290-3. doi: 10.2214/AJR.07.3198.

Abstract

Objective: The purpose of our study was to describe the MR signal characteristics of histologically proven liver adenomatosis in three patients using gadoxetic acid, a newly developed liver-specific MR contrast agent.

Conclusion: In all three patients, more than 100 liver adenomas revealed no metabolism of the new liver-specific contrast agent in the delayed phase. Because of absent or strongly reduced intracellular uptake of gadoxetic acid in all adenomas during delayed contrast-enhanced series, differentiation of adenomas from dysplastic or malignant lesions was not possible.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / pathology*
  • Adult
  • Contrast Media*
  • Female
  • Gadolinium DTPA*
  • Humans
  • Liver Neoplasms / pathology*
  • Magnetic Resonance Imaging*
  • Middle Aged

Substances

  • Contrast Media
  • gadolinium ethoxybenzyl DTPA
  • Gadolinium DTPA