Toll-like receptors

Curr Protoc Immunol. 2007 May:Chapter 14:14.12.1-14.12.13. doi: 10.1002/0471142735.im1412s77.

Abstract

This has led to the identification of several important roles for Toll receptors in mammals. This unit discusses mammalian Toll receptors (TLR1-10) that have an essential role in the innate immune recognition of microorganisms. Also discussed are TLR-mediated signaling pathways and antibodies that are available to detect specific TLRs.

Publication types

  • Review

MeSH terms

  • Adaptor Proteins, Vesicular Transport / genetics
  • Animals
  • Antibodies, Bacterial / immunology
  • Antibody Specificity
  • Bacterial Infections / immunology
  • Bacterial Proteins / immunology
  • Heat-Shock Proteins / immunology
  • Humans
  • Immunity, Innate*
  • Mice
  • Myeloid Differentiation Factor 88 / genetics
  • Nod Signaling Adaptor Proteins / genetics
  • Signal Transduction* / immunology
  • Toll-Like Receptors* / chemistry
  • Toll-Like Receptors* / classification
  • Toll-Like Receptors* / genetics
  • Toll-Like Receptors* / immunology
  • Toll-Like Receptors* / metabolism
  • Viral Proteins / immunology

Substances

  • Adaptor Proteins, Vesicular Transport
  • Antibodies, Bacterial
  • Bacterial Proteins
  • Heat-Shock Proteins
  • Myeloid Differentiation Factor 88
  • Nod Signaling Adaptor Proteins
  • TICAM1 protein, human
  • Toll-Like Receptors
  • Viral Proteins