Twenty eight cases (50 eyes) of chronic open-angle glaucoma and 21 cases (27 eyes) of optic neuritis were investigated with FM 100-hue test and panel D-15 test. In patients with optic neuritis, 70.37% and 85.19% of the affected eyes appeared abnormal in Panel D-15 test and FM 100-hue test respectively. The main defects were tritan-like in both of the tests. In patients with chronic open-angle glaucoma, 20% and 32% of the affected eyes had abnormal results in Panel D-15 test and FM 100-hue test respectively. The main defects were also tritan-like color vision defect. The total error scores of FM 100-hue test in patients with chronic open-angle glaucoma had no relation with the cup disc ratio and the area of peripheral visual field but had relation with the area of central visual field.