An efficient method for synthesising unsymmetrical silaketals: substrates for ring-closing, including macrocycle-closing, metathesis

Org Biomol Chem. 2008 May 21;6(10):1734-7. doi: 10.1039/b804769n. Epub 2008 Apr 10.

Abstract

Diisopropylsilyl ethers were activated with N-bromosuccinimide, and reacted with a fluorous-tagged alcohol, to yield tethered substrates for ring-closing metathesis reactions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cross-Linking Reagents / chemistry
  • Fluorine Compounds / chemistry
  • Macrocyclic Compounds / chemistry*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Silanes / chemical synthesis*
  • Silanes / chemistry
  • Stereoisomerism

Substances

  • Cross-Linking Reagents
  • Fluorine Compounds
  • Macrocyclic Compounds
  • Silanes