Preparation and characterization of bioglass/polyvinyl alcohol composite hydrogel

Biomed Mater. 2007 Jun;2(2):62-6. doi: 10.1088/1748-6041/2/2/002. Epub 2007 Mar 7.

Abstract

In order to form firm active fixation with the adjacent bone, a new kind of bioactive composite hydrogel was prepared with polyvinyl alcohol (PVA) and bioglass (BG) through ultrasonic dispersion, heat-high-pressure and freeze/thawed technique. A digital speckle correlation method (DSCM) was utilized to characterize the mechanical properties of the series of BG/PVA composites. Results showed that at different load pressures, the composite hydrogel displayed different displacement and deformation in the V field. Results also showed that an increase of PVA percentage (15-30 wt%) or of bioglass percentage (2-10 wt%) in composite hydrogel could lead to an increase in the elastic compression modulus. Scanning electron microscope results indicated that bioglass was uniformly dispersed in the BG/PVA composite hydrogel. The BG/PVA composite hydrogel shows a promising prospect as a new bionic cartilage implantation material.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bone Substitutes / chemistry*
  • Ceramics / chemistry*
  • Compressive Strength
  • Elasticity
  • Glass
  • Hydrogels / chemistry*
  • Materials Testing
  • Nanostructures / chemistry*
  • Nanostructures / ultrastructure*
  • Particle Size
  • Polyvinyl Alcohol / chemistry*
  • Surface Properties

Substances

  • Bone Substitutes
  • Hydrogels
  • bioactive glass 45S5
  • Polyvinyl Alcohol