Translational control: a new dimension in embryonic stem cell network analysis

Wing Y Chang; William L Stanford

doi:10.1016/j.stem.2008.04.009

Translational control: a new dimension in embryonic stem cell network analysis

Cell Stem Cell. 2008 May 8;2(5):410-2. doi: 10.1016/j.stem.2008.04.009.

Authors

Wing Y Chang¹, William L Stanford

Affiliation

¹ Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON M5S 3G9, Canada.

PMID: 18462690
DOI: 10.1016/j.stem.2008.04.009

Abstract

Systems biology studies have revealed transcriptional networks and proteomic signatures critical for embryonic stem cell (ESC) function. In this issue of Cell Stem Cell, Sampath et al. (2008) demonstrate that translation is also differentially controlled in undifferentiated versus differentiated ESCs.

Publication types

Comment

MeSH terms

Adaptor Proteins, Signal Transducing / genetics
Animals
Cell Differentiation*
Embryonic Stem Cells / cytology
Embryonic Stem Cells / physiology*
Mice
Protein Array Analysis
Protein Biosynthesis*
Protein Modification, Translational / genetics
Proteomics

Substances

Adaptor Proteins, Signal Transducing