Patch testing a patient with allergic contact hand dermatitis who is taking infliximab

David Rosmarin; Michelle Bush; Pamela L Scheinman

doi:10.1016/j.jaad.2008.02.016

Patch testing a patient with allergic contact hand dermatitis who is taking infliximab

J Am Acad Dermatol. 2008 Jul;59(1):145-7. doi: 10.1016/j.jaad.2008.02.016. Epub 2008 May 12.

Authors

David Rosmarin¹, Michelle Bush, Pamela L Scheinman

Affiliation

¹ Department of Dermatology, Tufts-New England Medical Center, Boston, Massachusetts, USA. [email protected]

PMID: 18468722
DOI: 10.1016/j.jaad.2008.02.016

Abstract

We report the case of a patient who developed allergic contact hand dermatitis while receiving infliximab infusions for psoriasis and psoriatic arthritis. Patch testing showed multiple positive allergens. To our knowledge, this is the first case report of successful patch testing in a patient receiving tumor necrosis factor-alpha (TNF-alpha) blockade therapy. TNF-alpha blockers do not necessarily suppress allergic contact hypersensitivity and are not an absolute contraindication to patch testing.

Publication types

Case Reports

MeSH terms

Antibodies, Monoclonal / therapeutic use*
Arthritis, Psoriatic / drug therapy
Dermatitis, Allergic Contact / diagnosis*
Dermatitis, Allergic Contact / etiology*
Dermatitis, Allergic Contact / prevention & control
Gloves, Protective
Hand Dermatoses / chemically induced*
Hand Dermatoses / diagnosis*
Hand Dermatoses / prevention & control
Humans
Infliximab
Male
Metallurgy
Metals
Middle Aged
Occupational Diseases / chemically induced*
Occupational Diseases / diagnosis*
Occupational Diseases / prevention & control
Occupational Exposure / analysis
Oils
Psoriasis / drug therapy
Skin Tests
Solvents
Tumor Necrosis Factor-alpha / antagonists & inhibitors

Substances

Antibodies, Monoclonal
Metals
Oils
Solvents
Tumor Necrosis Factor-alpha
Infliximab