Abstract
Many improvements have been made recently in the field of the ureteral smooth muscle pharmacology. After a brief summary on physiological basis, we review what is known about effects on ureter of different drugs class. In a second part, we review clinical applications for renal colic analgesia, calculi expulsive medical therapy, ESWL adjuvant treatment and preoperative treatment before retrograde access. There are now sufficient data on NSAID and alpha-blockers. beta-agonists, especially for beta3 selective ones, and topical drugs before retrograde access are interesting and should be further evaluated.
MeSH terms
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Adrenergic Agonists / pharmacology
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Adrenergic Agonists / therapeutic use
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Calcium Channel Blockers / pharmacology
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Calcium Channel Blockers / therapeutic use
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Cholinergic Antagonists / pharmacology
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Cholinergic Antagonists / therapeutic use
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Colic / therapy*
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Cyclooxygenase Inhibitors / pharmacology
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Cyclooxygenase Inhibitors / therapeutic use
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Humans
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Kidney Diseases / therapy*
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Lithotripsy
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Nitric Oxide Donors / pharmacology
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Nitric Oxide Donors / therapeutic use
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Peristalsis / physiology
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Ureter / physiology
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Ureteral Calculi / therapy*
Substances
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Adrenergic Agonists
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Calcium Channel Blockers
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Cholinergic Antagonists
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Cyclooxygenase Inhibitors
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Nitric Oxide Donors