Cryptogenic stroke in a boy with atrial septal defect and hyperhomocysteinemia

J Child Neurol. 2008 Sep;23(9):1070-1. doi: 10.1177/0883073808315416. Epub 2008 May 12.

Abstract

In children, clinical recognition of stroke and determination of its exact etiology are extremely difficult. The authors described a case of cryptogenic stroke in a 14-year-old-boy with asymptomatic atrial septal defect and hypercoagulable state. Paradoxical embolism was hypothesized as the responsible etiopathological mechanism. It is crucial to increase clinician awareness of stroke in children.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Age of Onset
  • Anticoagulants / therapeutic use
  • Blood Coagulation Disorders, Inherited / complications*
  • Blood Coagulation Disorders, Inherited / genetics
  • Cerebral Arteries / pathology
  • Cerebral Arteries / physiopathology
  • Diffusion Magnetic Resonance Imaging
  • Folic Acid / therapeutic use
  • Genetic Predisposition to Disease / genetics*
  • Heart Septal Defects, Atrial / complications*
  • Heart Septal Defects, Atrial / genetics
  • Hemianopsia / etiology
  • Hemianopsia / pathology
  • Hemianopsia / physiopathology
  • Humans
  • Hyperhomocysteinemia / complications*
  • Hyperhomocysteinemia / genetics
  • Infarction, Posterior Cerebral Artery / genetics*
  • Infarction, Posterior Cerebral Artery / pathology
  • Infarction, Posterior Cerebral Artery / physiopathology
  • Intracranial Embolism / genetics
  • Intracranial Embolism / pathology
  • Intracranial Embolism / physiopathology
  • Male
  • Occipital Lobe / blood supply
  • Occipital Lobe / pathology
  • Stroke / genetics*
  • Stroke / pathology
  • Stroke / physiopathology
  • Vitamin B 12 / therapeutic use

Substances

  • Anticoagulants
  • Folic Acid
  • Vitamin B 12