Isolation and characterization of a novel Francisella sp. from human cerebrospinal fluid and blood

J Clin Microbiol. 2008 Jul;46(7):2428-31. doi: 10.1128/JCM.00698-08. Epub 2008 May 21.

Abstract

We describe the isolation of a Francisella sp. from normally sterile sites in acutely ill patients in two different states within 2 years. Microbiologic and molecular analyses indicate that this organism represents a novel Francisella sp. Clinicians and microbiologists should be aware of this new potential pathogen, as infection may be more common than recognized.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Agglutination Tests
  • Bacteremia / microbiology
  • Bacterial Typing Techniques
  • Blood / microbiology*
  • Cerebrospinal Fluid / microbiology*
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • Female
  • Francisella / classification*
  • Francisella / genetics
  • Francisella / isolation & purification*
  • Humans
  • Infant
  • Male
  • Meningoencephalitis / microbiology
  • Molecular Sequence Data
  • Phylogeny
  • RNA, Ribosomal, 16S / genetics
  • Sequence Homology, Nucleic Acid

Substances

  • DNA, Bacterial
  • DNA, Ribosomal
  • RNA, Ribosomal, 16S

Associated data

  • GENBANK/EU031810
  • GENBANK/EU031811
  • GENBANK/EU031812
  • GENBANK/EU031813