[Sinonasal adenocarcinomas: our experience]

Acta Otorrinolaringol Esp. 2008 May;59(5):235-8. doi: 10.1016/s2173-5735(08)70229-1.
[Article in Spanish]

Abstract

Introduction and objectives: Sinonasal adenocarcinoma is a rare epithelial cancer of the nasal cavities and paranasal sinuses and exposure to sawdust particles is a strong aetiological factor.

Material and method: Seventy-nine patients (78 men and 1 woman) operated on between 1986 and 2002 were studied.

Results: In 62 patients (78.5 %) there was a history of exposure to wood dust. The clinical factors presenting statistical significance in the multivariate analysis with prognosis were: the exclusive invasion of the middle concha (as good prognosis), recurrence and invasion of the dura mater (as bad prognosis). The actuarial survival rate was 36 % at 5 years falling to 28 % at 10 years.

Conclusions: Exposure to wood dust, even over a short period of time, must be considered as a high risk factor for the development of a sinonasal adenocarcinoma. This tumour must be ruled out in all patients suffering any type of sinonasal pathology.

Publication types

  • English Abstract

MeSH terms

  • Adenocarcinoma / pathology*
  • Adult
  • Aged
  • Aged, 80 and over
  • Dust
  • Female
  • Humans
  • Male
  • Middle Aged
  • Paranasal Sinus Neoplasms / pathology*
  • Risk Factors
  • Wood

Substances

  • Dust