Femoral mycotic aneurysms require surgical treatment to prevent progressive sepsis and hemorrhage. Some surgeons recommend simple debridement and ligation of the femoral artery, whereas others recommend reconstruction in selected cases or all cases due to concerns about high risk of limb loss. In situ reconstruction has been discouraged due to concerns about anastomotic or graft disruption by persistent infection. However, the superficial femoral vein has been used successfully as an in situ replacement after removal of infected aortic prostheses. We present two patients with femoral mycotic aneurysms, both of whom were treated successfully with in situ reconstruction using autogenous superficial femoral vein.