Successful treatment of autoimmune pancreatitis complicated with autoimmune thrombocytopenia and interstitial pneumonia by prednisolone

Intern Med. 2008;47(11):1033-8. doi: 10.2169/internalmedicine.47.0803. Epub 2008 Jun 2.

Abstract

We report the second patient diagnosed with autoimmune pancreatitis complicated with autoimmune thrombocytopenia and interstitial pneumonia. The patient was treated with prednisolone and responded favorably. We demonstrated that anti-platelet (PLT) antibody of the patient was IgG4 and that it may react with HLA, not specific antigen, on both pancreas and PLT.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Autoantibodies / blood
  • Autoimmune Diseases / complications*
  • Autoimmune Diseases / diagnosis
  • Autoimmune Diseases / drug therapy*
  • Autoimmune Diseases / immunology
  • Blood Platelets / immunology
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunoglobulin G / blood
  • Lung Diseases, Interstitial / complications*
  • Lung Diseases, Interstitial / drug therapy*
  • Male
  • Pancreatitis / complications*
  • Pancreatitis / diagnosis
  • Pancreatitis / drug therapy*
  • Pancreatitis / immunology
  • Prednisolone / therapeutic use*
  • Purpura, Thrombocytopenic, Idiopathic / complications*
  • Purpura, Thrombocytopenic, Idiopathic / drug therapy*
  • Purpura, Thrombocytopenic, Idiopathic / immunology

Substances

  • Autoantibodies
  • Glucocorticoids
  • Immunoglobulin G
  • Prednisolone