Prenatal smoking and internalizing and externalizing problems in children studied from childhood to late adolescence

J Am Acad Child Adolesc Psychiatry. 2008 Jul;47(7):779-87. doi: 10.1097/CHI.0b013e318172eefb.

Abstract

Objective: To study whether prenatal smoking only relates to externalizing problems or whether it is associated with both internalizing and externalizing problems from childhood into late adolescence.

Method: Child Behavior Checklist-derived, parent-reported internalizing and externalizing problems of 396 children were longitudinally assessed at ages 5, 10 to 11, and 18 years. The influence of self-reported prenatal smoking on the course of internalizing and externalizing problems over these ages was assessed, controlling for the co-occurrence of internalizing and externalizing problems and co-occurring pre- and perinatal risk factors, demographic characteristics, maternal mental health, and child social and attention problems.

Results: Children whose mothers had smoked during pregnancy had increased levels of both internalizing and externalizing problems over the period of ages 5 to 18 years when compared with children whose mothers did not smoke during pregnancy. These associations remained significant after controlling internalizing for externalizing and vice versa and possible confounding variables.

Conclusions: Maternal smoking during pregnancy is a predictor of internalizing as well as externalizing psychopathology in offspring. The association between prenatal smoking and internalizing and externalizing problems persists throughout childhood and late adolescence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Causality
  • Child
  • Child Behavior Disorders / epidemiology
  • Child Behavior Disorders / etiology*
  • Female
  • Humans
  • Internal-External Control*
  • Longitudinal Studies
  • Male
  • Models, Statistical
  • Netherlands
  • Personality Assessment
  • Pregnancy
  • Prenatal Exposure Delayed Effects*
  • Risk Factors
  • Smoking / adverse effects*
  • Smoking / epidemiology