Tuneable pseudorotaxane formation between a biotin-avidin bioconjugate and CBPQT4+

Chem Commun (Camb). 2008 Jun 21:(23):2650-2. doi: 10.1039/b803856b. Epub 2008 May 8.

Abstract

A biotinylated 1,5-dialkoxynaphthalene derivative has been shown to have the ability to bind strongly to avidin and thus act as an artificial binding site for cyclobis(paraquat-p-phenylene) thereby facilitating the formation of a tuneable pseudorotaxane-based bioconjugate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Avidin / chemistry*
  • Binding Sites
  • Biotin / chemistry*
  • Electrons
  • Models, Chemical
  • Naphthalenes / chemistry*
  • Paraquat / analogs & derivatives
  • Paraquat / chemical synthesis*
  • Rotaxanes / chemical synthesis*
  • Spectrophotometry, Ultraviolet
  • Time Factors

Substances

  • Naphthalenes
  • Rotaxanes
  • Avidin
  • Biotin
  • Paraquat