Chemokines as pharmacological targets

Mini Rev Med Chem. 2008 Jun;8(7):638-46. doi: 10.2174/138955708784567386.

Abstract

Chemokines play a key role in immune processes by controlling leukocyte recruitment in physiological and pathological condition. This review discusses the regulation of the chemokine system, its role in human diseases, and its potential relevance as a new pharmacological target.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use
  • Chemokines / antagonists & inhibitors*
  • Chemokines / metabolism
  • Chemokines / physiology
  • Humans
  • Inflammation / immunology
  • Neoplasms / immunology

Substances

  • Anti-Inflammatory Agents
  • Chemokines