Abstract
T cells expressing the transcription factor Foxp3 have been shown to limit immune responses against microbes. In a recent issue of Science, Lund et al. support the idea that these cells can also coordinate the early entrance of innate cells at the effector site and therefore positively contribute to protective immunity.
Publication types
-
Research Support, N.I.H., Intramural
MeSH terms
-
Animals
-
Forkhead Transcription Factors / genetics
-
Forkhead Transcription Factors / immunology*
-
Herpes Simplex / immunology*
-
Herpes Simplex / virology
-
Humans
-
Mice
-
Simplexvirus / immunology
-
Simplexvirus / physiology
-
T-Lymphocytes / immunology*
Substances
-
Forkhead Transcription Factors
-
Foxp3 protein, mouse