Growth hormone inhibits the 11 beta-Hydroxysteroid dehydrogenase type 1 gene promoter activity via insulin-like growth factor I in HepG2 cells

Horm Metab Res. 2008 Apr;40(4):286-8. doi: 10.1055/s-2008-1058076.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 11-beta-Hydroxysteroid Dehydrogenase Type 1 / antagonists & inhibitors
  • 11-beta-Hydroxysteroid Dehydrogenase Type 1 / biosynthesis
  • 11-beta-Hydroxysteroid Dehydrogenase Type 1 / genetics*
  • Cell Line
  • Human Growth Hormone / pharmacology*
  • Humans
  • Insulin-Like Growth Factor I / physiology*
  • Luciferases / metabolism
  • Promoter Regions, Genetic / drug effects*
  • Protein Processing, Post-Translational / drug effects
  • RNA, Messenger / biosynthesis
  • RNA, Messenger / genetics
  • Reverse Transcriptase Polymerase Chain Reaction
  • beta-Galactosidase / metabolism

Substances

  • RNA, Messenger
  • Human Growth Hormone
  • Insulin-Like Growth Factor I
  • 11-beta-Hydroxysteroid Dehydrogenase Type 1
  • Luciferases
  • beta-Galactosidase