Long-term (up to 20 years) results of percutaneous balloon angioplasty of recurrent aortic coarctation without use of stents

Eur Heart J. 2008 Aug;29(16):2042-8. doi: 10.1093/eurheartj/ehn251. Epub 2008 Jun 10.

Abstract

Aims: To assess the efficacy, safety, and long-term results of the balloon angioplasty of recoarctation.

Methods and results: The angioplasty was performed in 99 consecutive patients aged 36 days to 32.6 years (median 268 days). Recoarctation to descending aorta diameter ratio increased from 0.44 (0.35/0.50) to 0.66 (0.57/0.77), P < 0.001. Systolic gradient was reduced from 34.0 (26.0/44.75) to 15.0 (8.25/27.0) mmHg, P < 0.001. In seven patients (7.1%) the procedure was ineffective. One patient (1%) with heart failure died within 24 h after a successful angioplasty and in another (1%) an intimal abruption necessitated surgical revision. The follow-up ranged up to 20.7 years (median 8.1 years). Actuarial probability of survival 20.7 years after the procedure was 0.91, and of reintervention-free survival was 0.44. Older age at the angioplasty was associated with a higher incidence of reinterventions (hazard ratio 1.057; 95% confidence interval 1.012-1.103; P = 0.010). The type of surgery and the recoarctation anatomy did not influence the outcome. In 69 patients aneurysm formation was studied by high-sensitive methods with only one positive finding per 462 patient-years.

Conclusion: Angioplasty is safe and effective regardless of the type of surgery used and the recoarctation anatomy. Older age at the angioplasty is associated with a higher incidence of reinterventions.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Angioplasty, Balloon* / adverse effects
  • Angioplasty, Balloon* / mortality
  • Aortic Coarctation / mortality
  • Aortic Coarctation / therapy*
  • Child
  • Child, Preschool
  • Electrocardiography
  • Female
  • Humans
  • Infant
  • Male
  • Recurrence
  • Retreatment
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome
  • Young Adult