Abstract
Organisms within the Mycobacterium avium complex (MAC) may have differential virulence. We compared 33 subjects with MAC pulmonary disease to 75 subjects with a single positive culture without disease. M. avium isolates were significantly more likely to be associated with MAC pulmonary disease (odds ratio = 5.14, 95% confidence interval = 1.25 to 22.73) than M. intracellulare.
Publication types
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Comparative Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Aged
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Case-Control Studies
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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DNA, Ribosomal Spacer / genetics*
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Female
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Humans
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Male
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Middle Aged
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Mycobacterium avium / genetics*
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Mycobacterium avium / pathogenicity*
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Mycobacterium avium Complex / genetics*
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Mycobacterium avium Complex / pathogenicity*
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Phylogeny
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Sequence Analysis, DNA
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Tuberculosis, Pulmonary / microbiology*
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Virulence
Substances
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DNA, Bacterial
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DNA, Ribosomal Spacer