Abstract
This case series describes the clinical and laboratory profile of 15 patients with tuberculosis (TB) HIV coinfection admitted to a referral centre in the Islamic Republic of Iran. Most of the patients (13) were male; the mean age was 36.9 years. Intravenous drug use was the route of transmission for all males and heterosexual intercourse for the 2 females; 12 patients had a history of imprisonment. All patients had pulmonary TB; 13 were smear-positive and all except 1 had atypical radiological presentation. Drug-induced hepatitis occurred in 3 patients and 12 had hepatitis C coinfection. Five patients died. The mean CD4 count was 229.2 (SD 199.5) cells/mm3 and 78.6% had CD4 count < 350. TB may be an AIDS-defining illness in this country.
MeSH terms
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AIDS-Related Opportunistic Infections / blood
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AIDS-Related Opportunistic Infections / complications
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AIDS-Related Opportunistic Infections / diagnosis
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AIDS-Related Opportunistic Infections / epidemiology*
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Adult
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Age Distribution
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CD4 Lymphocyte Count
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Chemical and Drug Induced Liver Injury / epidemiology
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Chi-Square Distribution
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Comorbidity
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Female
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Hepatitis C / epidemiology
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Hospitals, Urban
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Humans
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Iran / epidemiology
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Male
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Middle Aged
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Population Surveillance
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Prisoners / statistics & numerical data
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Referral and Consultation
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Risk Factors
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Sex Distribution
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Sexual Behavior
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Substance Abuse, Intravenous / complications
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Surveys and Questionnaires
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Tuberculosis, Pulmonary / blood
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Tuberculosis, Pulmonary / complications
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Tuberculosis, Pulmonary / diagnosis
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Tuberculosis, Pulmonary / epidemiology*