[Ma2 antibody and multiple mononeuropathies]

X Ayrignac; G Castelnovo; E Landrault; H Fayolle; Y-M Pers; J Honnorat; C Campello; D Figarella-Branger; P Labauge

doi:10.1016/j.neurol.2008.03.005

[Ma2 antibody and multiple mononeuropathies]

Rev Neurol (Paris). 2008 Jun-Jul;164(6-7):608-11. doi: 10.1016/j.neurol.2008.03.005. Epub 2008 May 19.

[Article in French]

Authors

X Ayrignac¹, G Castelnovo, E Landrault, H Fayolle, Y-M Pers, J Honnorat, C Campello, D Figarella-Branger, P Labauge

Affiliation

¹ Service de neurologie, CHU de Nîmes, 30029 Nîmes cedex, France.

PMID: 18565361
DOI: 10.1016/j.neurol.2008.03.005

Abstract

Anti-Ma2 antibodies belong to a family of onconeuronal antibodies that target proteins expressed in brain, testis and several tumors. Previously observed in patients presenting with limbic encephalitis, they seem to be associated with several other paraneoplastic syndromes. We report the case of a 73-year-old woman presenting sensory and motor neuropathy associated with non-small-cell lung cancer who had Ma2-antibodies.

Publication types

Case Reports

MeSH terms

Aged
Antibodies, Neoplasm / analysis*
Antigens, Neoplasm / immunology*
Biomarkers / analysis*
Carcinoma, Non-Small-Cell Lung / classification*
Carcinoma, Non-Small-Cell Lung / diagnostic imaging
Carcinoma, Non-Small-Cell Lung / immunology*
Female
Hereditary Sensory and Motor Neuropathy / diagnostic imaging
Hereditary Sensory and Motor Neuropathy / etiology*
Hereditary Sensory and Motor Neuropathy / immunology*
Humans
Lung Neoplasms / classification*
Lung Neoplasms / diagnostic imaging
Lung Neoplasms / immunology*
Magnetic Resonance Imaging
Nerve Tissue Proteins / immunology*
Radiography, Thoracic

Substances

Antibodies, Neoplasm
Antigens, Neoplasm
Biomarkers
Ma2 antigen
Nerve Tissue Proteins