Elevated plasma chromogranin-A concentrations in prostatic carcinoma

J Urol. 1991 Aug;146(2):358-61. doi: 10.1016/s0022-5347(17)37793-5.

Abstract

Chromogranin-A is considered a sensitive immunohistochemical tissue marker in neuroendocrine prostatic carcinoma. We report that the plasma chromogranin-A level was elevated in 48% of 25 patients with stage D2 prostate cancer, and suggest that this marker can be used to monitor the clinical course of these patients.

Publication types

  • Case Reports
  • Comparative Study
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Biomarkers / blood
  • Carcinoma / blood*
  • Chromogranin A
  • Chromogranins / blood*
  • Humans
  • Male
  • Middle Aged
  • Prostatic Neoplasms / blood*
  • Radioimmunoassay

Substances

  • Biomarkers
  • CHGA protein, human
  • Chromogranin A
  • Chromogranins