Abstract
We tested the effects of 5-Hz repetitive transcranial magnetic stimulation (rTMS) over the motor cortex in multiple sclerosis (MS) subjects with cerebellar symptoms. rTMS improved hand dexterity in cerebellar patients (n=8) but not in healthy subjects (n=7), as detected by a significant transient reduction of the time required to complete the nine-hole pegboard task. rTMS of the motor cortex may be a useful approach to treat cerebellar impairment in MS patients.
Publication types
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Clinical Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Cerebellar Ataxia / etiology
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Cerebellar Ataxia / physiopathology
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Cerebellar Ataxia / therapy*
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Cerebellum / physiopathology
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Female
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Hand / physiology
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Humans
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Male
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Middle Aged
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Motor Cortex / physiology*
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Movement / physiology
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Multiple Sclerosis, Relapsing-Remitting / complications
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Multiple Sclerosis, Relapsing-Remitting / physiopathology
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Multiple Sclerosis, Relapsing-Remitting / therapy*
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Transcranial Magnetic Stimulation*