Objective: To explore the relationship between chronic hepatitis B virus genotypes and clinical pathology.
Methods: HBV genotype was determined in 92 cases with chronic hepatitis B patients and the relationship between HBV genotypes and clinical, serological and histological data of the patients was analyzed.
Results: Sixteen cases were infected with HBV genotype B (17.4%), 71 with genotype C (77.2%), 3 with HBV classified as genotype B+C (3.2%) and in 2 (2.2%) cases HBV genotype was not confirmed. ALT level and HBV DNA load log value were (82.6+/-82) U/L, (84.7+/-71.5) U/L and (5.8+/-1.4), (5.9+/-1.5) respectively in genotypes B and C patients, in 8 cases of genotype C group liver cirrhosis was diagnosed, but no statistical significance was seen.
Conclusion: No significant differences in clinical, serological or histological data were detected between genotypes B and C patients.