The origins of blood: induction of hematopoietic stem cells from different sources

Cell Stem Cell. 2008 Jul 3;3(1):8-10. doi: 10.1016/j.stem.2008.06.008.

Abstract

Ex vivo hematopoiesis from embryonic sources offers exciting promises in basic research and medicine. In this issue of Cell Stem Cell, Ledran et al. (2008) describe human embryonic stem cell (hESC)-derived hematopoiesis, while Taoudi et al. (2008) define the origin of definitive hematopoietic stem cells (HSCs) from the mouse aorta-gonad-mesonephros (AGM) region.

Publication types

  • Comment

MeSH terms

  • Animals
  • Antigens, CD / physiology
  • Blood
  • Cadherins / physiology
  • Cell Differentiation
  • Hematopoiesis / physiology*
  • Hematopoietic Stem Cells / cytology*
  • Hematopoietic Stem Cells / physiology*
  • Humans
  • Leukocyte Common Antigens / physiology
  • Mice
  • Mice, Inbred NOD
  • Mice, SCID
  • Stromal Cells / cytology*
  • Stromal Cells / physiology*

Substances

  • Antigens, CD
  • Cadherins
  • cadherin 5
  • Leukocyte Common Antigens