Initial characterization of several actin genes in the parasitic nematode, Ascaris suum

Biochem Biophys Res Commun. 1991 Jul 31;178(2):578-85. doi: 10.1016/0006-291x(91)90147-y.

Abstract

Southern hybridization data suggest a large actin gene family in Ascaris suum. Our genomic reconstruction experiment indicated that it consists of 50-75 members. Polymorphism was uncovered in the actin genes or in their surrounding sequences. From the genomic library 5 nonoverlapping actin clones were isolated and characterized.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Actins / genetics*
  • Animals
  • Ascaris / genetics*
  • Cloning, Molecular
  • DNA / genetics
  • DNA / isolation & purification
  • Genomic Library
  • Nucleic Acid Hybridization
  • Polymorphism, Genetic*
  • Restriction Mapping

Substances

  • Actins
  • DNA