Endothelial dysfunction and vascular inflammation in type 2 diabetes: interaction of AGE/RAGE and TNF-alpha signaling

Am J Physiol Heart Circ Physiol. 2008 Aug;295(2):H475-6. doi: 10.1152/ajpheart.00644.2008. Epub 2008 Jul 3.
No abstract available

Publication types

  • Editorial
  • Comment

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / therapeutic use
  • Cardiovascular Agents / therapeutic use
  • Diabetes Mellitus, Type 2 / drug therapy
  • Diabetes Mellitus, Type 2 / metabolism
  • Diabetes Mellitus, Type 2 / physiopathology*
  • Diabetic Angiopathies / drug therapy
  • Diabetic Angiopathies / metabolism
  • Diabetic Angiopathies / physiopathology*
  • Endothelium, Vascular / drug effects
  • Endothelium, Vascular / metabolism
  • Endothelium, Vascular / physiopathology*
  • Glycation End Products, Advanced / metabolism*
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Inflammation / drug therapy
  • Inflammation / metabolism
  • Inflammation / physiopathology*
  • Receptor for Advanced Glycation End Products
  • Receptors, Immunologic / metabolism*
  • Signal Transduction*
  • Tumor Necrosis Factor-alpha / metabolism*

Substances

  • Anti-Inflammatory Agents
  • Cardiovascular Agents
  • Glycation End Products, Advanced
  • Hypoglycemic Agents
  • Receptor for Advanced Glycation End Products
  • Receptors, Immunologic
  • Tumor Necrosis Factor-alpha