Simultaneous squamous cell carcinoma with leiomyosarcoma of the larynx

Auris Nasus Larynx. 2009 Apr;36(2):239-43. doi: 10.1016/j.anl.2008.05.012. Epub 2008 Jul 9.

Abstract

Objective: To present the first reported case of a simultaneous squamous cell carcinoma with a leiomyosarcoma of the larynx, our treatment of the patient, and the 9-month follow-up results.

Study design: Case study.

Methods: Review of diagnostic studies, the operative technique, and the patient's chart for the 9-month period after treatment.

Results: A case with double laryngeal tumors with simultaneous evolution but different histological patterns is described. The squamous cell carcinoma and leiomyosarcoma involved both the vocal cords and the anterior commissure. A partial laryngectomy was performed, and the patient has been free of disease for 9 months.

Conclusions: Multiple laryngeal tumors are exceedingly rare. To our knowledge, no previous reports of a simultaneous squamous cell carcinoma and a leiomyosarcoma of the larynx have been reported. Both tumors were not invasive in this case, so conservation surgery was feasible.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy
  • Carcinoma, Squamous Cell / diagnosis*
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / surgery
  • Follow-Up Studies
  • Humans
  • Laryngeal Mucosa / pathology
  • Laryngeal Neoplasms / diagnosis*
  • Laryngeal Neoplasms / pathology
  • Laryngeal Neoplasms / surgery
  • Laryngectomy
  • Laryngoscopy*
  • Leiomyosarcoma / diagnosis*
  • Leiomyosarcoma / pathology
  • Leiomyosarcoma / surgery
  • Magnetic Resonance Imaging*
  • Male
  • Neoplasms, Multiple Primary / diagnosis*
  • Neoplasms, Multiple Primary / pathology
  • Neoplasms, Multiple Primary / surgery
  • Vocal Cords / pathology
  • Vocal Cords / surgery