Drug-induced renal toxicity. Help in recognizing offending agents

Postgrad Med. 1991 Aug;90(2):241-4, 247-8. doi: 10.1080/00325481.1991.11701021.

Abstract

Drug-induced kidney disease is common, especially in hospitalized patients, and prompt recognition of the various nephrotoxic syndromes is important because many are reversible. Risk factors should be assessed before patients are given an agent that may cause acute renal failure (eg, nonsteroidal anti-inflammatory drug, aminoglycoside antibiotic, angiotensin-converting enzyme inhibitor, radiocontrast agent). Discontinuation of the responsible drug is often the only necessary therapy.

Publication types

  • Review

MeSH terms

  • Aminoglycosides
  • Angiotensin-Converting Enzyme Inhibitors / adverse effects*
  • Anti-Bacterial Agents / adverse effects*
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
  • Contrast Media / adverse effects*
  • Education, Medical, Continuing
  • Hemodynamics
  • Humans
  • Kidney Diseases / chemically induced*
  • Kidney Diseases / epidemiology
  • Kidney Diseases / physiopathology
  • Risk Factors

Substances

  • Aminoglycosides
  • Angiotensin-Converting Enzyme Inhibitors
  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents, Non-Steroidal
  • Contrast Media