Argyria attributed to silvadene application in a patient with dystrophic epidermolysis bullosa

Dermatol Online J. 2008 Apr 15;14(4):9.

Abstract

Argyria is most commonly reported in association with prolonged ingestion of silver-containing medicaments. This case illustrates the rather unique case of development of argyria following application of silver sulfadiazine in a patient with epidermolysis bullosa.

Publication types

  • Case Reports

MeSH terms

  • Administration, Cutaneous
  • Adult
  • Anti-Infective Agents, Local / administration & dosage
  • Anti-Infective Agents, Local / adverse effects*
  • Argyria / blood
  • Argyria / etiology*
  • Argyria / pathology
  • Epidermolysis Bullosa Dystrophica / drug therapy*
  • Epidermolysis Bullosa Dystrophica / pathology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Risk Factors
  • Silver / blood*
  • Silver Sulfadiazine / administration & dosage
  • Silver Sulfadiazine / adverse effects*
  • Skin / pathology
  • Skin Absorption

Substances

  • Anti-Infective Agents, Local
  • Silver
  • Silver Sulfadiazine