Mortality secondary to fulminant hepatic failure in patients with prior resolution of hepatitis B virus infection in Japan

Clin Infect Dis. 2008 Sep 1;47(5):e52-6. doi: 10.1086/590968.

Abstract

Hepatitis B virus (HBV) reactivation in patients with resolved HBV infection was found in 23 (4%) of 552 newly hepatitis B surface antigen-positive patients in Japan. Because one-fourth of cases develop into fulminant hepatic failure and mortality is 100%, management of HBV reactivation in patients with resolved HBV infection should be discussed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antiviral Agents / therapeutic use
  • Female
  • Hepatitis B / complications*
  • Hepatitis B / drug therapy
  • Humans
  • Japan / epidemiology
  • Liver Failure, Acute / epidemiology
  • Liver Failure, Acute / mortality*
  • Male
  • Middle Aged
  • Prevalence
  • Virus Activation*
  • Young Adult

Substances

  • Antiviral Agents