Two new holostan-type triterpene glycosides from the sea cucumber Bohadschia marmorata JAEGER

Chem Pharm Bull (Tokyo). 2008 Aug;56(8):1207-11. doi: 10.1248/cpb.56.1207.

Abstract

Two new holostan-type triterpene glycosides, 17-hydroxy fuscocineroside B (1) and 25-hydroxy fuscocineroside B (2), together with a known triterpene glycoside, fuscocineroside B (3) were isolated from the sea cucumber Bohadschia marmorata JAEGER. The structures of the new triterpene glycosides were elucidated on the basis of spectroscopic analyses and chemical reactions. Compounds 1 and 3 showed considerable antifungal activities against six strains.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antifungal Agents / isolation & purification*
  • Antifungal Agents / pharmacology
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Molecular Structure
  • Sea Cucumbers / chemistry*
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*
  • Triterpenes / pharmacology

Substances

  • Antifungal Agents
  • Glycosides
  • Triterpenes
  • fuscocineroside B