Diagnostic dilemmas and clinical correlates of mixed states in bipolar disorder

J Clin Psychiatry. 2008 May;69(5):e13. doi: 10.4088/jcp.0508e13.

Abstract

Patients with bipolar disorder frequently have varying degrees of mixed states rather than pure episodic manic and depressive episodes. However, DSM-IV-TR and ICD-10 criteria do not fully account for patients' varying presentations; currently, there is no consensus on whether mixed states is a distinct, categorically different type of mania or whether it is a transitional state between depression and mania. Inconsistent diagnostic criteria can be problematic for clinicians when treating patients.

MeSH terms

  • Bipolar Disorder / diagnosis*
  • Consensus*
  • Depressive Disorder, Major / diagnosis*
  • Diagnosis, Differential
  • Diagnostic and Statistical Manual of Mental Disorders
  • Humans
  • International Classification of Diseases