Obesity and persisting sleep apnea after adenotonsillectomy in Greek children

Chest. 2008 Dec;134(6):1149-1155. doi: 10.1378/chest.08-1056. Epub 2008 Aug 8.

Abstract

Background: The relative importance of obesity and adenotonsillar hypertrophy in the pathogenesis of obstructive sleep-disordered breathing (SDB) in childhood is unclear. Adenotonsillectomy (AT) for SDB is not always curative, and obese children are at increased risk for residual disease postoperatively.

Objective: The aim of this investigation was to assess the efficacy of AT as treatment for SDB in obese and nonobese children.

Methods: Children with adenoidal and/or tonsillar hypertrophy who underwent AT for the treatment of SDB underwent polysomnography preoperatively and postoperatively. A body mass index (BMI) z score of > 1.645 was used to define obesity. The achievement of a postoperative obstructive apnea-hypopnea index (OAHI) of less than one episode per hour (ie, the cure of SDB) was the primary outcome measure.

Results: Twenty-two obese children (mean [+/- SD] age, 5.8 +/- 1.8 years; mean BMI z score, 2.6 +/- 0.8; mean OAHI, 9.5 +/- 9.7 episodes per hour) and 48 nonobese children (mean age, 6.9 +/- 2.6 years; mean BMI z score, 0.09 +/- 1.1; OAHI, 6 +/- 5.4 episodes per hour) were recruited. After surgery, obese and nonobese subjects did not differ in the efficacy of AT (postoperative OAHI of less than one episode per hour, 22.7% vs 25% of subjects, respectively; p > 0.05). The presence of obesity, adenoidal or tonsillar hypertrophy, gender, and postoperative BMI change were not significant predictors of SDB cure.

Conclusions: Obesity does not necessarily predict an unfavorable outcome of AT as treatment for SDB.

Publication types

  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenoidectomy*
  • Adenoids / pathology*
  • Body Mass Index
  • Child
  • Child, Preschool
  • Female
  • Greece
  • Humans
  • Hypertrophy / complications
  • Hypertrophy / pathology
  • Hypertrophy / surgery
  • Male
  • Obesity / complications*
  • Obesity / pathology
  • Obesity / surgery
  • Palatine Tonsil / pathology*
  • Risk Factors
  • Sleep Apnea, Obstructive / complications
  • Sleep Apnea, Obstructive / pathology
  • Sleep Apnea, Obstructive / surgery*
  • Tonsillectomy*
  • Treatment Outcome