Superficial genitourinary abscesses in children: emergence of methicillin resistant Staphylococcus aureus

J Urol. 2008 Oct;180(4):1472-5. doi: 10.1016/j.juro.2008.06.055. Epub 2008 Aug 16.

Abstract

Purpose: The prevalence of methicillin resistant Staphylococcus aureus is increasing. However, little is known about methicillin resistant S. aureus in the genitourinary tract, particularly in children. We assessed the incidence of pediatric genitourinary methicillin resistant S. aureus superficial abscess requiring surgical intervention.

Materials and methods: We reviewed the records of all children undergoing surgical debridement of superficial abscess at a single institution between 1995 and 2007. We assessed surgical site, organism identity, patient comorbidity, methicillin resistant S. aureus risk factors, number of procedures and patient outcome.

Results: Surgical debridement of a superficial genitourinary abscess was performed in 60 children. Patient age ranged from 29 days to 17 years (median 3 years). A single debridement was generally curative, with only 5 patients (8.3%) requiring more than 1 procedure. One patient (1.7%) died of sepsis postoperatively due to Pseudomonas infection. One patient had myelomeningocele, 1 had undergone renal transplant and 2 were undergoing chemotherapy at the time of debridement. None of these 3 patients had a methicillin resistant S. aureus infection. Methicillin resistant S. aureus was more common in the groin/genitalia and less common in the perineum (p = 0.007). The incidence of methicillin resistant S. aureus increased during the study period, accounting for none of 40 infections between 1995 and 2003, and 8 of 20 (40%) from 2004 to 2007 (p <0.001).

Conclusions: Methicillin resistant S. aureus has become the predominant organism causing pediatric superficial genitourinary abscesses at our institution, accounting for three-quarters of all surgically managed infections in the last 2 years. Methicillin resistant S. aureus was more common at the groin and genitalia. One debridement was generally curative, and patient morbidity was low with aggressive treatment.

MeSH terms

  • Abscess / drug therapy*
  • Abscess / epidemiology
  • Abscess / microbiology
  • Abscess / pathology
  • Abscess / surgery
  • Adolescent
  • Age Distribution
  • Child
  • Child, Preschool
  • Cohort Studies
  • Debridement / methods
  • Female
  • Female Urogenital Diseases / drug therapy*
  • Female Urogenital Diseases / epidemiology
  • Female Urogenital Diseases / microbiology
  • Follow-Up Studies
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Male
  • Male Urogenital Diseases / drug therapy*
  • Male Urogenital Diseases / epidemiology
  • Male Urogenital Diseases / microbiology
  • Methicillin Resistance*
  • Microbial Sensitivity Tests
  • Probability
  • Retrospective Studies
  • Risk Assessment
  • Sex Distribution
  • Staphylococcal Infections / diagnosis
  • Staphylococcal Infections / drug therapy*
  • Staphylococcal Infections / epidemiology*
  • Staphylococcus aureus / drug effects
  • Staphylococcus aureus / isolation & purification
  • Treatment Outcome