De novo collapsing glomerulopathy in a renal allograft recipient

Saudi J Kidney Dis Transpl. 2008 Sep;19(5):793-5.

Abstract

Collapsing glomerulopathy (CG), characterized histologically by segmental/global glomerular capillary collapse, podocyte hypertrophy and hypercellularity and tubulo-interstitial injury; is characterized clinically by massive proteinuria and rapid progressive renal failure. CG is known to recur in renal allograft and rarely de novo. We report de novo CG 3 years post-transplant in a patient who received renal allograft from haplo-identical type donor.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Complement C4b / analysis
  • Epithelial Cells / pathology
  • Humans
  • Hyperplasia
  • Hypertension / complications
  • Kidney Cortex Necrosis / pathology*
  • Kidney Failure, Chronic / etiology
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation / pathology*
  • Kidney Tubules / pathology
  • Male
  • Peptide Fragments / analysis
  • Reoperation
  • Waiting Lists

Substances

  • Peptide Fragments
  • Complement C4b
  • complement C4d