[Expression and its significance of eosinophil major basic protein in chronic rhinosinusitis]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2008 May;22(10):454-5.
[Article in Chinese]

Abstract

Objective: To evaluate the expression of eosinophil major basic protein (MBP) in chronic rhinosinusitis (CRS) and discuss the role of MBP in the pathogenesis in CRS.

Method: Thirty-eight nasal mucus obtained from CRS patients were used to detect the expression of MBP by Elisa assay. Thirty nasal mucus samples from health people were used as control.

Result: The expression of MBP of nasal mucus obtained from CRS patients was obviously higher than that of nasal mucus obtained from control. There was significant statistical difference (P < 0.01).

Conclusion: MBP was involved in the formation of CRS.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Blood Proteins / metabolism*
  • Case-Control Studies
  • Chronic Disease
  • Eosinophil Major Basic Protein
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mucus / metabolism*
  • Nasal Mucosa / metabolism
  • Proteoglycans / metabolism*
  • Sinusitis / metabolism*
  • Sinusitis / pathology

Substances

  • Blood Proteins
  • Proteoglycans
  • PRG2 protein, human
  • Eosinophil Major Basic Protein