Embryonal rhabdomyosarcoma of the uterine cervix in a 41-year-old woman treated with radical hysterectomy and adjuvant chemotherapy

Mary Ann Sanders; Mary Gordinier; Sameer S Talwalkar; Grace D Moore

doi:10.1016/j.ygyno.2008.07.016

Embryonal rhabdomyosarcoma of the uterine cervix in a 41-year-old woman treated with radical hysterectomy and adjuvant chemotherapy

Gynecol Oncol. 2008 Dec;111(3):561-3. doi: 10.1016/j.ygyno.2008.07.016. Epub 2008 Aug 24.

Authors

Mary Ann Sanders¹, Mary Gordinier, Sameer S Talwalkar, Grace D Moore

Affiliation

¹ Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, Kentucky, USA.

PMID: 18725166
DOI: 10.1016/j.ygyno.2008.07.016

Abstract

Background: Cervical embryonal rhabdomyosarcoma (ERMS) mostly affects young girls. The current treatment protocols are based on trials done on patients under 21 years old. ERMS in women over 40 is rare, and studies on treatment and outcome are limited.

Case: We report a case of a 41 year-old woman with cervical ERMS who was treated with radical hysterectomy followed by chemotherapy. She is currently disease-free.

Conclusion: Cervical ERMS in women over the age of 40 can be treated using protocols established for the pediatric population.

Publication types

Case Reports

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Chemotherapy, Adjuvant
Cyclophosphamide / administration & dosage
Dactinomycin / administration & dosage
Female
Humans
Hysterectomy
Rhabdomyosarcoma / drug therapy*
Rhabdomyosarcoma / pathology
Rhabdomyosarcoma / surgery*
Uterine Cervical Neoplasms / drug therapy*
Uterine Cervical Neoplasms / pathology
Uterine Cervical Neoplasms / surgery*
Vincristine / administration & dosage

Substances

Dactinomycin
Vincristine
Cyclophosphamide