Necrotizing fasciitis

Br J Surg. 1991 Jul;78(7):838-40. doi: 10.1002/bjs.1800780722.

Abstract

Ten cases of necrotizing fasciitis are reviewed. Three patients died but only two of these deaths were due to uncontrolled septicaemia. All isolated organisms were sensitive to a combination of piperacillin and ampicillin which we now regard as the initial antibiotic combination of choice. Prompt and aggressive surgical debridement remains the cornerstone of management.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Ampicillin / therapeutic use
  • Combined Modality Therapy
  • Debridement
  • Drug Therapy, Combination / therapeutic use
  • Fasciitis / complications
  • Fasciitis / drug therapy
  • Fasciitis / surgery*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Necrosis
  • Piperacillin / therapeutic use
  • Sepsis / etiology

Substances

  • Ampicillin
  • Piperacillin