[Efficacy of ozeltamivir (Tamiflu) in adult influenza on the epidemic rise of morbidity in Russia in the 2006-2007 season]

Vopr Virusol. 2008 Jul-Aug;53(4):23-6.
[Article in Russian]

Abstract

The paper gives the results of using ozeltamivir in patients with influenza during the epidemic upsurge of morbidity in Russia in the 2006-2007 season. Comparative analysis of nucteotide sequences of viral strains isolated from the patients taking ozeltamivir revealed no marker mutations determining the resistance to this chemical.

Publication types

  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Antiviral Agents / administration & dosage
  • Antiviral Agents / therapeutic use*
  • Capsules
  • Cytopathogenic Effect, Viral / drug effects
  • Drug Administration Schedule
  • Drug Resistance, Viral / genetics
  • Female
  • Humans
  • Influenza A Virus, H1N1 Subtype* / drug effects
  • Influenza A Virus, H1N1 Subtype* / genetics
  • Influenza A Virus, H1N1 Subtype* / isolation & purification
  • Influenza A Virus, H3N2 Subtype* / drug effects
  • Influenza A Virus, H3N2 Subtype* / genetics
  • Influenza A Virus, H3N2 Subtype* / isolation & purification
  • Influenza, Human / drug therapy*
  • Influenza, Human / epidemiology
  • Influenza, Human / virology
  • Male
  • Middle Aged
  • Moscow / epidemiology
  • Mutation
  • Oseltamivir / administration & dosage
  • Oseltamivir / therapeutic use*
  • Treatment Outcome

Substances

  • Antiviral Agents
  • Capsules
  • Oseltamivir