A new lignan glucoside from the stems of Callicarpa japonica Thunb. var. luxurians Rehd

J Nat Med. 2009 Jan;63(1):86-90. doi: 10.1007/s11418-008-0289-1. Epub 2008 Sep 10.

Abstract

A new lignan glucoside (1) was isolated from the stems of Callicarpa japonica Thunb. var. luxurians Rehd. (Verbenaceae), along with six known lignan glucosides and three known triterpenoids. The chemical structure of 1 was characterized as (+)-lyoniresinol 3 alpha-O-(6''-3,5-dimethoxy-4-hydroxybenzoyl)-beta-D-glucopyranoside on the basis of spectroscopic data. In addition, the radical-scavenging effect of four lignans on the stable free radical 1,1-diphenyl-2-picrylhydrazyl was examined. Among the tested compounds, three compounds, including 1, showed almost the same scavenging activity as that of alpha-tocopherol.

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Biphenyl Compounds / chemistry
  • Callicarpa / chemistry*
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification
  • Glucosides / chemistry*
  • Glucosides / isolation & purification
  • Hydrazines / chemistry
  • Lignans / chemistry*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Picrates
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Stems / chemistry*
  • Triterpenes / chemistry

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Free Radical Scavengers
  • Glucosides
  • Hydrazines
  • Lignans
  • Picrates
  • Plant Extracts
  • Triterpenes
  • 1,1-diphenyl-2-picrylhydrazyl