[The diagnosis of bladder carcinomas by NMR tomography: an improvement with Gd-DTPA?]

Rofo. 1991 Aug;155(2):117-22. doi: 10.1055/s-2008-1033231.
[Article in German]

Abstract

85 patients suffering from urinary bladder carcinoma were examined by magnetic resonance imaging in a prospective study. Following precontrast diagnosis, 15 patients were given an intravesicular application of gadolinium-DTPA (Gd-DTPA). Another 35 patients received an intravenous bolus of GD-DTPA. A diagnostic advantage was achieved in only 2 of 15 tumours by using intravesicular contrast application. Compared to the precontrast diagnosis, a 14% improvement from 69% (precontrast) to 83% (contrast medium) was seen with Gd-DTPA applied intravenously in the diagnosis of the tumour stage. The diagnostic gain lies in the improved tumour recognition, the improved demarcation of papillary, non-muscle-infiltrating tumours and in the more definite diagnosis of infiltration into neighbouring organs and the pelvic wall. Demarcation of perivesicular fatty infiltration is rendered more difficult by Gd-DTPA.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Administration, Intravesical
  • Carcinoma / diagnosis*
  • Carcinoma / epidemiology
  • Carcinoma / pathology
  • Contrast Media* / administration & dosage
  • Drug Evaluation
  • Female
  • Gadolinium DTPA
  • Gadolinium* / administration & dosage
  • Humans
  • Injections, Intravenous
  • Magnetic Resonance Imaging / instrumentation
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Imaging / statistics & numerical data
  • Male
  • Neoplasm Staging
  • Organometallic Compounds* / administration & dosage
  • Pentetic Acid* / administration & dosage
  • Prospective Studies
  • Urinary Bladder Neoplasms / diagnosis*
  • Urinary Bladder Neoplasms / epidemiology
  • Urinary Bladder Neoplasms / pathology

Substances

  • Contrast Media
  • Organometallic Compounds
  • Pentetic Acid
  • Gadolinium
  • Gadolinium DTPA