Abstract
A class 2 integron was found in an Escherichia coli isolate mediating a urinary tract infection. Unlike other class 2 integrons from pathogens, the encoded IntI2 protein was functional. The integron possessed a dfrA14 cassette, and a second novel cassette in which a lipoprotein signal peptidase gene is predicted.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Drug Resistance, Multiple, Bacterial / genetics
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Escherichia coli / enzymology
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Escherichia coli / genetics*
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Escherichia coli / isolation & purification
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Escherichia coli / pathogenicity*
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Escherichia coli Infections / microbiology*
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Escherichia coli Proteins / genetics*
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Genes, Bacterial
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Humans
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Integrases / genetics*
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Integrons*
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Molecular Sequence Data
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Plasmids / genetics
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Recombination, Genetic
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Urinary Tract Infections / microbiology*
Substances
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Escherichia coli Proteins
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InTI2 protein, E coli
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Integrases