Myofiber properties of mouse mylohyoid muscle in the growth period

Zoolog Sci. 2008 Aug;25(8):806-10. doi: 10.2108/zsj.25.806.

Abstract

The mouse mylohyoid muscle belongs to the mastication-related suprahyoid muscle group. It shows a plate-like morphology and forms the mouth floor. There have been no reports on the characteristics of the mouse mylohyoid muscle fibers, and especially on their functional role during ingestion action, and many points remain unclear. We examined the mouse mylohyoid muscle at both the transcriptional and protein levels by RT-PCR, immunohistochemistry, and Western Blotting. MyHC-2b, which is expressed in almost all head and neck muscles and is thought to play a role in rapid mastication movement, was not detected in the mouse mylohyoid muscle. This result suggests that the mouse mylohyoid muscle has a special function and does not directly function during ingestion.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blotting, Western
  • Immunohistochemistry
  • Mastication / genetics
  • Mastication / physiology*
  • Masticatory Muscles / physiology*
  • Mice
  • Mice, Inbred ICR
  • Muscle Contraction / genetics
  • Muscle Contraction / physiology*
  • Muscle Fibers, Skeletal / physiology*
  • Myosin Heavy Chains / genetics
  • Myosin Heavy Chains / metabolism*
  • Protein Isoforms / genetics
  • Protein Isoforms / metabolism*
  • RNA, Messenger / genetics
  • Reverse Transcriptase Polymerase Chain Reaction

Substances

  • Protein Isoforms
  • RNA, Messenger
  • Myosin Heavy Chains