Cost-effectiveness of different strategies for amplified Mycobacterium tuberculosis direct testing for cases of pulmonary tuberculosis

J Clin Microbiol. 2008 Nov;46(11):3811-2. doi: 10.1128/JCM.01682-08. Epub 2008 Sep 17.

Abstract

We conducted a decision analysis to assess and compare four algorithms for amplified Mycobacterium tuberculosis direct (MTD) testing of respiratory specimens in terms of cost-effectiveness. The most cost-effective strategy was one in which smear-positive specimens but not smear-negative specimens were diluted prior to MTD testing.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Cost-Benefit Analysis
  • Humans
  • Mycobacterium tuberculosis / genetics
  • Mycobacterium tuberculosis / isolation & purification*
  • Nucleic Acid Amplification Techniques / economics*
  • Nucleic Acid Amplification Techniques / methods*
  • Tuberculosis, Pulmonary / diagnosis*
  • Tuberculosis, Pulmonary / microbiology