Is there a role for Tc-99m (V) DMSA scintigraphy in ischemic colitis?

World J Gastroenterol. 2008 Sep 21;14(35):5432-5. doi: 10.3748/wjg.14.5432.

Abstract

Aim: To evaluate the role of pentavalent Tc-99m dimercaptosuccinic acid [Tc-99m (V) DMSA] in the diagnosis of ischemic colitis.

Methods: Fourteen patients with endoscopically and histologically confirmed ischemic colitis were included in the study. Tc-99m (V) DMSA scintigraphy was performed within 2 d after colonoscopy. Images were considered positive when an area of increased activity was observed in the region of interest and negative when no abnormal tracer uptake was detected.

Results: In 3 out of the 14 patients, Tc-99m (V) DMSA images showed moderate activity in the bowel. The scintigraphic results corresponded with the endoscopic findings. In the other 11 patients, no abnormal tracer uptake was detected in the abdomen.

Conclusion: Besides the limited number of patients, Tc-99m (V) DMSA could not be considered as a useful imaging modality for the evaluation of ischemic colitis.

Publication types

  • Evaluation Study

MeSH terms

  • Aged
  • Colitis, Ischemic / diagnosis
  • Colitis, Ischemic / diagnostic imaging*
  • Colonoscopy
  • False Negative Reactions
  • Female
  • Humans
  • Male
  • Radionuclide Imaging
  • Radiopharmaceuticals
  • Sensitivity and Specificity
  • Technetium Tc 99m Dimercaptosuccinic Acid*

Substances

  • Radiopharmaceuticals
  • Technetium Tc 99m Dimercaptosuccinic Acid