A case of acute promyelocytic leukemia presenting with a nonleukemic granulocytic sarcoma of the ovary, with subsequent development of acute myeloid leukemia associated with t(8;21)

Leuk Res. 2009 Apr;33(4):580-2. doi: 10.1016/j.leukres.2008.08.008. Epub 2008 Sep 19.

Authors

Xingbing Wang, Huilan Liu, Zhiwei Wu, Xiucai Xu, Xin Chen, Zhimin Zhai, Zimin Sun

PMID: 18804280
DOI: 10.1016/j.leukres.2008.08.008

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Antineoplastic Agents / adverse effects
Chromosome Aberrations
Chromosomes, Human, Pair 21 / genetics
Chromosomes, Human, Pair 8 / genetics
Female
Humans
Leukemia, Myeloid, Acute / chemically induced
Leukemia, Myeloid, Acute / genetics
Leukemia, Myeloid, Acute / pathology*
Leukemia, Promyelocytic, Acute / drug therapy
Leukemia, Promyelocytic, Acute / pathology*
Neoplasms, Second Primary / chemically induced
Neoplasms, Second Primary / genetics
Neoplasms, Second Primary / pathology*
Oncogene Proteins, Fusion / metabolism
Ovarian Neoplasms / drug therapy
Ovarian Neoplasms / pathology*
Reverse Transcriptase Polymerase Chain Reaction
Sarcoma, Myeloid / drug therapy
Sarcoma, Myeloid / pathology*
Translocation, Genetic

Substances

Antineoplastic Agents
Oncogene Proteins, Fusion
promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein