Dynamic imaging of contrast enhancement in brain tumors

Magn Reson Med. 1991 Jun;19(2):293-8. doi: 10.1002/mrm.1910190217.

Abstract

Gadolinium-DTPA has been shown to be a good probe for demonstrating defects in the blood-brain barrier, but it has a rapid rate of elimination so that peak circulating levels are short-lived. In this study ultrafast echo-planar imaging has been used in combination with a bolus injection of gadolinium-DTPA to evaluate perfusion within brain tumors and to assess the degree of disruption of the blood-brain barrier. The temporal profile of enhancement may allow discrimination between different tumor types.

MeSH terms

  • Blood-Brain Barrier
  • Brain / blood supply
  • Brain Neoplasms / blood supply
  • Brain Neoplasms / diagnosis*
  • Contrast Media*
  • Gadolinium DTPA
  • Gadolinium*
  • Humans
  • Image Enhancement / methods*
  • Magnetic Resonance Imaging / methods*
  • Microcirculation
  • Organometallic Compounds*
  • Pentetic Acid*

Substances

  • Contrast Media
  • Organometallic Compounds
  • Pentetic Acid
  • Gadolinium
  • Gadolinium DTPA